【摘要】背景：医学教育改革是目前医学教育不断进取和探索的重要方式，近年来，系统整合课程的设置与落实，带来了许多有关利弊的讨论。按照教育部对于医学教育的实施规划要求，医学生的发展应该注重临床与基础结合、人文与医技共荣式的发展。因此，临床整合课程的实施具有现实意义，其有效性在不同的培养单位有所差异，因此其方法对于实际课程教学的效果有待进一步探索和论证。目的：研究某大型三甲医院临床医学院以器官系统为中心的医学诊断学整合课程对医学生学习效果的影响，从而对整合课程的教学与改革提供经验与方向。方法：回顾性分析实行整合课程教学改革之前的两届学生与实行整合课程教学改革之后的两届学生的学习情况并进行对比，比较其学习效果的差异（采用t检验）。结果：共调查2010、2011级临床医学本科生58人，2012、2013级临床医学本科生79人，其中整合课程教改后，学生的综合能力发展有了显著的提高，专业方面获奖情况、学习成绩与前者相比有进步（P<0.05）。结论：临床整合课程对医学生的综合全面发展，以及知识掌握和自主思考方面有促进作用。
　　【关键词】整合课程  临床医学  教育改革  医学  教学效果
　　【Abstract】Background：The medical curriculum reform is an important way for medical education to continuously advance and explore. In recent years， the establishment and implementation of medical integrated courses has brought a lot of discussion on the pros and cons of medical integration course for medical education. In accordance with the implementation requirements of the Ministry of Education for medical education，， the development of medical students should focus on the combination of clinical skills and scientific research and the common prosperity of humanities and medical technology. Objective：To study the influence of the integrated course of medical diagnostics centered on organ system on the learning effect of medical students in a First？鄄class Hospital at Grade three. Which will provide experience and direction for the teaching and reform of the integrated courses. Methods： Retrospectively analyzing and comparing the learning situation of the students before the implementation of the integrated curriculum teaching reform and the students after the implementation of the integrated curriculum teaching reform.  Results：A total of 58 Clinical medicine undergraduate from 2010 and 2011 were surveyed， and 79 Clinical medicine undergraduate from 2012 and 2013 were surveyed. After the integration of the curriculum reform， the students？蒺 comprehensive ability has been significantly improved. In terms of professional aspects， the latter？蒺s awards and academic achievements have a greater advantage than the former.  Conclusion：The medical integration curriculum has a positive effect on the comprehensive development， knowledge and independent thinking of medical students.
　　【Keywords】Integrated course; Clinical medicine; Education reform; Medicine; Learning effects
　　【基金項目】同济大学2017-2018年教学改革研究与建设项目（项目编号：1500104166）;南通大学2016年度教学改革研究课题（项目编号：2016B106）。
　　【中图分类号】R-4;G434 【文献标识码】A 【文章编号】2095-3089（2020）52-0057-03